Plataforma gen\u00f3mica para c\u00e1ncer de mama en estadio inicial, con test pron\u00f3stico validado para determinar el riesgo de recurrencia a 10 a\u00f1os en pacientes postmenop\u00e1usicas con c\u00e1ncer de mama estadio inicial, receptores hormonales positivos y Her2 negativo.<\/p>\n
Se realiza en la pieza de biopsia quir\u00fargica (cuadrantectom\u00eda\/mastectom\u00eda) en pacientes con estadio inicial. El an\u00e1lisis determina el subtipo molecular (luminal A, luminal B, basal like, Her2+) y calcula el score de riesgo de recurrencia (ROR) combinando informaci\u00f3n gen\u00f3mica y cl\u00ednica como tama\u00f1o tumoral y proliferaci\u00f3n celular. Con la informaci\u00f3n del estado ganglionar, se clasifica al paciente en grupo de riesgo alto, intermedio o bajo.<\/p>\n
Este test ayuda en la toma de decisiones terap\u00e9uticas, identificando a pacientes HR+\/HER2- que no necesitan quimioterapia (grupo de bajo riesgo). Los subtipos tumorales predicen la sensibilidad a la quimioterapia en la enfermedad temprana HR+\/HER2-, y la plataforma gen\u00f3mica es m\u00e1s sensible y espec\u00edfica que la inmunohistoqu\u00edmica.<\/p>\n","protected":false},"excerpt":{"rendered":"
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